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Pediatric Clinical Pharmacology and Toxicology

The following services are provided by this division within the Department of Pediatrics:

Clinical Pharmacology

Complete assessment and evaluation of all problems concerning either pharmacodynamics (i.e., therapeutic selection, efficacy, safety, drug interactions, adverse drug effects) and clinical pharmacokinetics (i.e., adjustments of drug dosing for patients with renal and/or hepatic compromise, bioavailability assessment) are performed. Additionally, pharmacokinetic optimization of drug therapy for specialized patients (i.e., transplant patients receiving cyclosporine, patients receiving IVIG, warfarin and anticonvulsant agents) is available either on a consultative basis or through the Therapeutic Drug Monitoring Service. Drug information services relative to pediatric clinical pharmacology are also available to medical staff members. In addition, the Clinical Pharmacology Service provides consultation for tapers of opiods and benzodiazepines in critically ill children.

Clinical Toxicology

Consultation regarding the identification, emergency management, clinical care and follow-up evaluation for accidental and intentional ingestions is available on a 24-hour basis. Specialized services for chronic intoxications common to pediatrics (i.e., lead poisoning) are also provided on a consultative basis. The service is also available to provide expertise in the management of snake and spider envenomations.

The Section on Pediatric Clinical Pharmacology is staffed 24 hours a day, 7 days a week by board certified (or eligible) professionals in Clinical Pharmacology.


Phone: 501-364-1418
Fax: 501-364-3654


Laura P. James, MD


Henry C. Farrar, MD
Pediatric Clinical Pharmacology, Toxicology and
Emergency Medicine

Thomas G. Wells, MD
Pediatric Clinical Pharmacology and Nephrology

Cindy D. Stowe, PharmD
Pediatric Clinical Pharmacology

Holly D. Maples, PharmD
Pediatric Clinical Pharmacology

Dean Roberts, PhD
Analytical Toxicology

Kendrea Muldrew, PharmD
Pediatric Clinical Pharmacology

Amber Morgan, MD
Pediatric Clinical Pharmacology, Toxicology

Catherine O'Brien, PharmD
Pediatric Clinical Pharmacology

Note: This clinic is available to your child by physician referral. Talk with your child's physician and tell him/her you would like to be referred to ACH. Have the doctor contact the Arkansas Children's Hospital Appointment Center to make a referral at 501-364-4000. If your child does not have a regular physician, please call 501-364-4000 and we will be happy to recommend one in your area.

Arkansas Children's Hospital
1 Children's Way
Little Rock, AR 72202-3591

Call: 501-364-1100
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