Pediatric Clinical Pharmacology and Toxicology

The following services are provided by this division within the Department of Pediatrics:

Clinical Pharmacology

Complete assessment and evaluation of all problems concerning either pharmacodynamics (i.e., therapeutic selection, efficacy, safety, drug interactions, adverse drug effects) and clinical pharmacokinetics (i.e., adjustments of drug dosing for patients with renal and/or hepatic compromise, bioavailability assessment) are performed. Additionally, pharmacokinetic optimization of drug therapy for specialized patients (i.e., transplant patients receiving cyclosporine, patients receiving IVIG, warfarin and anticonvulsant agents) is available either on a consultative basis or through the Therapeutic Drug Monitoring Service. Drug information services relative to pediatric clinical pharmacology are also available to medical staff members. In addition, the Clinical Pharmacology Service provides consultation for tapers of opiods and benzodiazepines in critically ill children.

Clinical Toxicology

Consultation regarding the identification, emergency management, clinical care and follow-up evaluation for accidental and intentional ingestions is available on a 24-hour basis. Specialized services for chronic intoxications common to pediatrics (i.e., lead poisoning) are also provided on a consultative basis. The service is also available to provide expertise in the management of snake and spider envenomations.

The Section on Pediatric Clinical Pharmacology is staffed 24 hours a day, 7 days a week by board certified (or eligible) professionals in Clinical Pharmacology.

Appointments:

Phone: 501-364-1418 
Fax: 501-364-3654

Director:

Laura P. James, MD 
501-364-1418

Staff:

Henry C. Farrar, MD 
Pediatric Clinical Pharmacology, Toxicology and 
Emergency Medicine 
501-364-1418 

Thomas G. Wells, MD 
Pediatric Clinical Pharmacology and Nephrology 
501-364-1418 

Cindy D. Stowe, PharmD 
Pediatric Clinical Pharmacology 
501-364-1418 

Holly D. Maples, PharmD 
Pediatric Clinical Pharmacology 
501-364-1418 

Dean Roberts, PhD 
Analytical Toxicology 
501-364-1418 

Kendrea Muldrew, PharmD 
Pediatric Clinical Pharmacology 
501-364-1418 

Amber Morgan, MD 
Pediatric Clinical Pharmacology, Toxicology 
501-364-1418 

Catherine O'Brien, PharmD 
Pediatric Clinical Pharmacology 
501-364-1418

Note: This clinic is available to your child by physician referral. Talk with your child's physician and tell him/her you would like to be referred to ACH. Have the doctor contact the Arkansas Children's Hospital Appointment Center to make a referral at 501-364-4000. If your child does not have a regular physician, please call 501-364-4000 and we will be happy to recommend one in your area.