Alan J. Tackett, PhD

Professor of Biochemistry & Molecular Biology, Pediatrics and Pathology, University of Arkansas for Medical Sciences
Proteomics Facility Director
Phone:  (501) 686-8152

Research Overview

Dr. Tackett’s laboratory focuses on histone epigenetic mechanisms that regulate gene transcription and that are coupled to melanoma progression. He uses a suite of techniques in studies including proteomics of human biopsies, immunohistochemistry, cell culture, tumorigenicity assays, ChIPseq, and biochemical and proteomic approaches for analyses of protein complexes and cutting-edge mass spectrometry for the analysis of histone post-translational modifications. The Proteomics Facility provides a unique environment to support discovery-based studies like proteomics as well as hypothesis-driven studies performed in cell culture and with skin biopsies. In addition to melanoma work, Dr. Tackett’s team develops new technologies for epigenetic studies such as tools for detection of in vivo protein interactions and quantitative assays for histone modifying proteins.

Complete List of Published Work in MyBibliography

http://www.ncbi.nlm.nih.gov/sites/myncbi/1N3GnuyxsdzQL/bibliograpahy/46332325/public/?sort=date&direction=ascending