Sam Smith, M.D. is the Boyd Family Professor of Surgery at the University of Arkansas for Medical Sciences. Dr. Smith is the Section Chief for the Pediatric General Surgery and Surgeon in Chief at Arkansas Children's Hospital. Dr. Smith received his M.D. in 1980 from the University of Arkansas for Medical Sciences, and completed a residency in General Surgery at UAMS in 1985. Dr. Smith went on to complete fellowships in Pediatric Surgery and Surgical Critical Care at the University of Pittsburgh and Children's Hospital of Pittsburgh. Dr. Smith joined the faculty at Arkansas Children's Hospital in 1992. Dr. Smith has co-authored more than 90 papers and 17 Book Chapters. He is board certified in Pediatric Surgery, General Surgery, and Surgical Critical Care. Dr. Smith has been listed in Best Doctors in America and Arkansas since the year 2000. He is a member of the American College of Surgeons, American College of Critical Care Medicine, American Pediatric Surgery Association, American Academy of Pediatrics, and Southern Surgical Society.

Dr. Smith’s research interests include the gut as a source of infection in infants. The development of the normal intestinal bacteria or flora is frequently altered in infants that are hospitalized in the newborn period particularly premature infants. This leads to systemic infections and in some cases the development of necrotizing enterocolitis. Necrotizing enterocolitis is particularly dangerous disease which can lead to significant intestinal loss, sepsis, and possible death. Dr. Smith and his team have working to better understand how alteration in the intestinal flora and other factors can be altered to prevent or lessen the severity of necrotizing enterocolitis.

Key publications

Mehall JR, Kite CA, Saltzman DA, Wallett T, Jackson RJ, Smith SD. Prospective study of the incidence and complications of bacterial contamination of enteral feeding in neonates. J Pediatr Surg. 2002 Aug; 37(8):1177-82.

McVay MR, Boneti C, Habib CM, Keller JE, Kokoska ER, Jackson RJ, Smith SD. Formula fortified with live probiotic culture reduces pulmonary and gastrointestinal bacterial colonization and translocation in a newborn animal model. J Pediatr Surg. 2008 Jan; 43(1):25-9.

Bozeman AP, Dassinger MS, Birusingh RJ, Burford JM, Smith SD. An animal model of necrotizing enterocolitis (NEC) in preterm rabbits. Fetal Pediatr Pathol. 2013 Apr;32(2):113-22.

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