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SATB2 International Clinic

Arkansas Children’s Hospital hosts the only dedicated multidisciplinary clinic for the SATB2-associated syndrome in the United States. Participants can anticipate to undergo a comprehensive evaluation by our experienced SATB2 team.

2020 SATB2 Clinic

Arkansas Children's Hospital is excited to announce that starting June 2020, the SATB2-associated syndrome clinically will be offered quarterly. For more information, please contact the SATB2 clinic coordinator, Katie Bosanko at kbbonsanko@uams.edu

Websites: satb2gene.com | satb2gene.org 


SATB2-associated syndrome (SAS) is a genetic disorder characterized by:

  • developmental delay/intellectual disability with absent or limited speech development
  • behavioral problems
  • abnormalities of the palate (roof of the mouth) and teeth

Changes in the SATB2 gene cause this syndrome. Common types of gene changes are mutations (misspellings), deletions (pieces missing), or duplications (pieces extra) in the SATB2 gene. SAS has also been labeled “Glass syndrome” (OMIM #612313) after Dr. Glass who described a patient with a deletion in chromosome 2 back in 1989. Similarly, other patients with deletions in this area have been labeled “2q33.1 microdeletion syndrome” or “2q32 deletion syndrome”. 

Yuri Zarate, M.D., is a clinical geneticist at Arkansas Children’s Hospital and has initiated a project to collect clinical information on patients with SAS no matter how the SATB2 gene is changed (deletions, duplications, or mutations) to increase knowledge of this condition.

Currently, more than 150 families are enrolled in the study. Parents and clinicians are encouraged to contact Dr. Zarate for further questions and to consider enrollment in his study.

For more information about SATB2, including FAQs, visit: satb2gene.com

Resources

Dr. Yuri Zarate - SATB2 SpecialistContact

Yuri Zarate, M.D.,MBA
Associate Professor, Section of Genetics and Metabolism
University of Arkansas for Medical Sciences
Arkansas Children’s Hospital
1 Children’s Way Slot 512-22
Little Rock, AR 72202
Phone: 501-364-1926
Fax: 501-364-1564

Katie Bosanko, MS, CGC
Genetic Counselor
Arkansas Children's Hospital
1 Children's Way Slot 512-22
Little Rock, AR  72202
Phone: 501-364-4057
Fax: 501-364-1564