Study Overview

The Happy Tummies Study is a nutrition research study designed to look at the gut health and immune systems of infants that are fed exclusively either breast-milk or Similac Advance formula.

Mom and baby will attend 5 study visits, starting when baby is 1 month old.

At the 1-month and 2-month old visits we will provide Similac Advance formula, ask about baby’s nutrition, and obtain some body measurements on baby. These visits will each last about an hour.

At the 3- month old visit, we will ask medical history questions, obtain some body temperature and composition measurements on baby, and perform blood, urine, stool, and cheek swab collection. This visit will last about 4 hours. We will also ask mom to complete a 3-day food record.

At the fourth visit, we will ask mom to bring back the completed food records and stool samples.To thank you for your participation, a 3-month supply of Similac Advance formula and diapers will be provided.

The last visit will be when baby is 12 month old. At this visit we will have you come after baby has received their vaccinations and ask you to bring those records with you. We will perform blood, urine, stool, and cheek swab collection. An additional 3-month supply of diapers will be proved to thank you for your participation at this visit.

Mom and baby will attend 2 study visits when baby is 3 months old, and one visit when baby is 12 months old.

At the 3 month old visit we will ask medical history questions, obtain some body temperature and composition measurements on baby, and perform a blood, urine, stool, and cheek swab collection. The visit will last about 4 hours. We will also ask mom to complete a 3- day food record prior to the visit and provide a breast milk sample if breast-feeding.

At the second visit we will ask mom to bring back the completed food records, breast milk sample, and stool samples. To thank you for your participation, a 3-month supply of diapers will be provided.

At the 12 month old visit, we will have you come after baby has received their vaccinations and ask you to bring those records with you. We will perform blood, urine, stool, and cheek swab collection. We will also ask you to provide a breastmilk sample if you are still breast-feeding. An additional 3-month supply of diapers will be provided to thank you for your participation at this visit.

Study Eligibility

Infants less than 1 month old to be fed Similac Advance, or infants exclusively breastfeeding at about 3 months old.

Contact Information

For questions about this study, call 501-364-3309 or send an email to acncstudies@archildrens.org.