ELECTRA Pregnancy Study

Study Overview

Are you pregnant or postpartum and taking a CFTR modulator medication, such as Trikafta®? More people with cystic fibrosis are becoming pregnant while taking CFTR modulators. However, we still need more information about these medicines during pregnancy and breastfeeding. Researchers at Arkansas Children’s Hospital are doing a study to better understand how modulator medicines move through the body. What we learn may help doctors better care for pregnant people with CF and their babies in the future.

Who can join?

You may be able to join if you are:

• Female 18 or older
• Pregnant or recently post-partum
• On a CFTR modulator medicine like Trikafta®

What will happen during the study?

• Get information about your health, pregnancy, diet and medications
• Check how well your lungs work and collect sweat
• Get blood samples during pregnancy and after delivery
• Get breast milk samples, if available
• Collect small blood samples and growth checks for your baby after birth

The study team will explain each visit and answer your questions before you decide if you want to join. Participants will be compensated up to $250 for each prenatal visit and up to $90 for each visit thereafter.

Study Locations

• Arkansas Children's Hospital
• University of Arkansas for Medical Sciences
• University of Alabama at Birmingham
• University of California San Francisco
• The Ohio State University
• Northwestern University
• Case Western Reserve University
• University of Pittsburgh Medical Center

Contact Information

Bianca Johnson, Dr., PH
Clinical Research Supervisor, Pulmonary
501-364 - 5954
Johnsonb2@archildrens.org

PI Information

Dr. Jennifer S. Guimbellot, M.D., Ph.D.
(Section Chief, Pulmonary & Sleep Medicine)
Clinic Bio: Jennifer Guimbellot, M.D.
Research Bio: Pulmonary Pharmacology Group | UAMS Dept of Pediatrics