Borderline (Decreased) Activity of Biotinidase Enzyme: 40.0-50.0

  • Do this test NOW:
    • Submit a repeat HL-11 newborn screen specimen to the health department.

  • For more information, refer to the health department (ADH) letter that was faxed to you and information at the ADH website.  Call 501-364-4050 to speak with the Newborn Screening Coordinator or page at 501-364-1100.

Abnormal activity of Biotinidase enzyme: <40.0

  • Do this test NOW:
    • Serum Biotinidase Assay
    • Start infant on Biotin 5 mg orally daily or 2.5 mg orally twice daily.

  • For more information, refer to the health department (ADH) letter that was faxed to you and information at the ADH website.  Call 501-364-4050 to speak with the Newborn Screening Coordinator or page at 501-364-1100.