Hematology and Oncology Studies | Arkansas Children's Research Institute

Clinical Trial

SoNIC Teens Study: Sickle Cell Neurological Impact and Cognition in Teenagers

Learn more about SoNIC Teens Study: Sickle Cell Neurological Impact and Cognition in Teenagers. Through this study, we are working to better understand how SCD impacts the developing brain.

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Clinical Trial

PARPAML: A Phase 1 Protocol for Relapsed Pediatric AML to Determine the Safety and Efficacy of the PARP Inhibitor Talazoparib in Combination with Chemotherapy

The purpose of this study is to find out what effects study treatment with talazoparib in combination with conventional chemotherapy agents topotecan and gemcitabine has on you and your cancer.

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Clinical Trial

A Phase II Study of Naxitamab Added to Induction Therapy for Subjects with Newly Diagnosed High-Risk Neuroblastoma

This multicenter clinical trial is studying the safety and efficacy of the monoclonal antibody naxitamab, combined with standard induction treatment, in children newly diagnosed with high-risk neuroblastoma.

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Clinical Trial

A PHASE I/IIA STUDY OF 2-HYDROXYOLEIC ACID IN PEDIATRIC PATIENTS WITH MALIGNANT GLIOMA AND OTHER ADVANCED SOLID TUMORS

This study is a phase I/IIa study of 2-Hydroxyoleic acid in pediatric patients with malignant glioma and other advanced solid tumors.

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Clinical Trial

A Phase 2 Study to Assess the Safety and Efficacy of Cobimetinib in Refractory Langerhans Cell Histiocytosis, LCH-Associated Neurodegenerative Disease, and Other Histiocytic Disorders

Learn more about a Phase 2 Study to assess the safety and efficacy of Cobimetinib in Refractory Langerhans Cell Histiocytosis, LCH-Associated Neurodegenerative Disease.

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Clinical Trial

BCC 016 A Phase II Trial of Eflornithine/DFMO as Maintenance Therapy for Molecular High Risk/Very High Risk and Relapsed/Refractory Medulloblastoma

This study seeks to evaluate how well the DFMO works to prevent relapse in patients with high risk and very high risk medulloblastoma.

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Clinical Trial

Phase II Trial of Tipifarnib and Naxitamab for Relapsed/Refractory Neuroblastoma

This study initially aims to evaluate the safety and tolerability of tipifarnib when combined with naxitamab in pediatric and young adult patients.

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Clinical Trial

TINI 2: Total Therapy for Infants with Acute Lymphoblastic Leukemia II

The goals of this study are to increase disease clearance and sustain deep remission through the use of the immunotherapy agent, blinatumomab.

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Clinical Trial

STReNGth & Outpatient Exercise Regimen in Acute Lymphoblastic Leukemia/Lymphoblastic Lymphoma

This study assesses short-term benefits like improved physical function and how regular, structured physical activity during therapy may promote long-term health and reduce chronic complications in survivorship.

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Clinical Trial

UNITCALL Study

We are looking for children between the ages of 3 and 10 to help us learn about typical brain development. Learn more about the Unitcall clinical trial.

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